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Prostate Specific Antigen (PSA)

PSA test for prostate cancer screening and monitoring prostate health in men.

Details:

Prostate Specific Antigen (PSA) is a protein produced by the prostate gland. The PSA test measures the level of PSA in the blood and is used primarily for prostate cancer screening and monitoring.

Test Types

  • Total PSA
  • Free PSA
  • Free/Total PSA Ratio
  • PSA Velocity (rate of change over time)
  • PSA Density (PSA relative to prostate size)

Clinical Applications

  • Screen for prostate cancer
  • Monitor prostate cancer treatment
  • Detect prostate cancer recurrence
  • Evaluate enlarged prostate (BPH)
  • Assess prostatitis (prostate inflammation)

Interpretation

  • Normal: Generally less than 4.0 ng/mL
  • Borderline: 4.0 to 10.0 ng/mL
  • High: Greater than 10.0 ng/mL
  • Note: PSA levels increase with age; reference ranges may vary

Important Notes

  • Elevated PSA does not always mean cancer
  • Can be elevated due to BPH, prostatitis, or other causes
  • Should be interpreted with other clinical findings
  • Free PSA ratio helps distinguish cancer from benign conditions

Sample Type

  • Whole Blood

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